What are the most common ototoxic drugs?

The most common reported ototoxic drugs in clinical use are aminoglycoside antibiotics, macrolide antibiotics, salicylates, chemotherapeutic agents such as cisplatin, loop diuretics, antimalarials, non-steroidal anti-inflammatory drugs (NSAIDs), quinine, and acetaminophen (Rybak & Ramkumar, 2007; Tabuchi et al., 2011; …

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What are the names of ototoxic drugs?

bleomycine (Blenoxane) • bromocriptine (Parlodel) • carboplatinum (Carboplatin) • cisplatin (Platinol) • methotrexate (Rheumatrex) • nitrogen mustard (Mustargen) • vinblastin (Velban) • vincristine (Oncovin) (The ototoxic effects can be minimized by carefully monitoring blood levels.)

Which drug is toxic as well as ototoxic?

It is well established that many drugs, such as the aminoglycoside antibiotics and the chemotherapeutic drug cisplatin, are capable of inducing both nephrotoxicity and ototoxicity.

Which drugs cause ringing in the ears?

Medications known to cause tinnitus include nonsteroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics, cancer drugs, water pills (diuretics), antimalarial drugs and antidepressants.

What is the best medicine for tinnitus?

Medications for Tinnitus

For some, treatment with low doses of anti-anxiety drugs — such as Valium or antidepressants such as Elavil — help reduce tinnitus. The use of a steroid placed into the middle ear along with an anti-anxiety medicine called alprazolam has been shown to be effective for some people.

Which antihistamine is best for tinnitus?

Some types of antihistamines that have been used to treat tinnitus in people with allergies include: chlorpheniramine. meclizine. terfenadine.

Is Tylenol an ototoxic drug?

Ototoxic over-the-counter medications: pain relievers
Common pain relievers like aspirin (also used for heart health), ibuprofen (Advil/Motrin), naproxen (Aleve), and acetaminophen (Tylenol), make up a surprising category of ototoxic drugs that can harm your hearing.

What are five common medications that are potentially ototoxic and may cause hearing loss?

The ototoxic medications include loop diuretics, nonsteroidal anti-inflammatory drugs, antibiotics, chemotherapeutic agents, quinine, and acetaminophen in this study.

What medications can cause hearing loss?

Medicines That Cause Hearing Loss

Aspirin, when large doses (8 to 12 pills a day) are taken.
Non-steroidal anti-inflammatory drugs (NSAIDs).
Certain antibiotics.
Loop diuretics. They’re used to treat high blood pressure and heart failure.
Certain medicines used to treat cancer.

What is the new treatment for tinnitus?

15, 2020 — In the largest clinical trial of its kind, researchers show that combining sound and electrical stimulation of the tongue can significantly reduce tinnitus, commonly described as ‘ringing in the …

What vitamin deficiency causes tinnitus?

[23] Vitamin B12 deficiency may cause the demyelination of neurons in the cochlear nerve, resulting in hearing loss and tinnitus.

What exercises help tinnitus?

Tinnitus exercises
Inhale and tighten only the muscles you are concentrating on for 8 seconds. Release them by suddenly letting go. Let the tightness and pain flow out of the muscles while you slowly exhale. Continue this progression systematically from your head down to the feet.

Does Benadryl help with tinnitus?

Antihistamines are sometimes prescribed for tinnitus, but at this time results for the effectiveness of antihistamines for tinnitus patients is inconclusive.

What painkillers are ototoxic?

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

diclofenac (Voltaren)
etocolac (Lodine)
fenprofen (Nalfon)
ibuprofen (Motrin, Advil, Nuprin, etc.)
indomethacin (Indocin)
naproxen (Naprosyn, Anaprox, Aleve)
piroxicam (Feldene)
sulindac (Clinoril)

Is caffeine ototoxic?

In vivo research showed that 120 mg/ kg caffeine injection caused hearing loss by damaging the organ of Corti, stria vascularis, and spiral ganglion neurons. RNA-seq results suggested that SGK1 might play a vital role in ototoxicity.

What blood pressure medications cause hearing loss?

Diuretics medicines such as furosemide or bumetanide used to treat high blood pressure and heart failure can also cause hearing loss. The medicines are more likely to result in hearing loss if you take more than one at a time, ASHA reports.

Is there a cure for tinnitus in 2022?

Currently, there is no cure for tinnitus. In other words, there is treatment but no scientifically-proven approach to completely eliminate tinnitus. However, tinnitus can be improved for many individuals if the treatments are sensibly selected and properly carried out.

Is there a pill to stop tinnitus?

However, although the economic and emotional impact of tinnitus is large, there are currently no FDA-approved drugs to treat this condition.

Does vitamin D increase tinnitus?

Our findings suggest that a large proportion of tinnitus patients suffers from vitamin D deficiency and that the vitamin D level correlates with tinnitus impact.

What is the best pill to take for tinnitus?

When I press my neck my tinnitus stops?

The last maneuver of gentle neck pressure, which occludes the ipsilateral jugular vein, is particularly important. If the sound stops, it is almost certainly due to venous sinus stenosis or another venous sinus cause, such as dehiscent jugular plate or diverticulum.

Is there a cure for tinnitus 2022?

What antihistamine is best for tinnitus?

What pain reliever does not cause tinnitus?

Low-dose aspirin use not associated with tinnitus risk
(All participants were between ages 31 to 48 and did not have tinnitus when they enrolled in the study). Past research has also found a link between regular use of aspirin, NSAIDs and acetaminophen and hearing loss in men.

Which vitamins can cause tinnitus?

What Vitamin Deficiency Causes Ringing in the Ears?

Tinnitus is a common problem that affects the inner ear.
These symptoms can be exacerbated during times of stress or fatigue and lead to frustration, irritability and depression.
Tinnitus has been linked to vitamin B12 and vitamin D deficiencies.