What is multifocal epithelial hyperplasia?
Multifocal epithelial hyperplasia (MEH) is an uncommon disease characterized by the proliferation on the oral mucosa of multiple papulonodular lesions, which are smooth, soft on palpation and generally asymptomatic (1–5).
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How do you get Heck’s disease?
Heck’s disease is predominantly found in children and adolescents with indigenous heritage and has a variable female predilection 2. Heck’s disease often affects multiple members of given family. This familial tendency may be related to either genetic susceptibility or HPV transmission between family members 3.
What is focal epithelial hyperplasia?
Focal epithelial hyperplasia (FEH), or Heck’s disease, is a rare disease of the oral mucosa; it is mostly found in children or young adults who are immunosuppressed and who live in regions with low socioeconomic status. It is characterized by asymptomatic papules on the oral mucosa, gingiva, tongue, and lips.
How is epithelial hyperplasia treated?
Treatment options for multifocal epithelial hyperplasia comprise surgical removal, laser excision, electrocautery, cryotherapy and topical agents such as imiquimod, retinoic acid or trichloroacetic acid.
What causes epithelial hyperplasia?
Epithelial Pathology
Multifocal epithelial hyperplasia is a squamous epithelial proliferation mainly caused by human papillomavirus (HPV) types 13 and 32. Potential contributory factors include genetic predisposition, crowded living conditions, poor hygiene, malnutrition, and human immunodeficiency virus infection.
Is Heck’s disease an STD?
Focal epithelial hyperplasia or Heck’s disease, is a rare viral infection of the oral mucosa caused by human papillomavirus. The frequency of this disease varies widely from one geographic region to another. In Caucasians there have been only few cases reported.
Is Heck’s disease contagious?
Communities with close living spaces appear to exhibit more reported cases. Personal hygiene, nutrition deficiency, and oral hygiene deficiency have been noted as well and may play a role in spreading the virus. The virus is very contagious and easily spread.
What hyperplasia means?
(HY-per-PLAY-zhuh) An increase in the number of cells in an organ or tissue. These cells appear normal under a microscope. They are not cancer, but may become cancer. Enlarge.
Is hyperplasia precancerous?
Atypical hyperplasia is a precancerous condition that affects cells in the breast. Atypical hyperplasia describes an accumulation of abnormal cells in the milk ducts and lobules of the breast. Atypical hyperplasia isn’t cancer, but it increases the risk of breast cancer.
How do you treat Heck’s disease?
We report the successful topical treatment of focal epithelial hyperplasia (Heck’s disease) with interferon-beta (Fiblaferon gel). Topical treatment with interferon-beta appears to be an effective, simple, non-invasive, cheap and low-risk alternative to other invasive or surgical therapeutic modalities.
Can hyperplasia be cured?
Most cases of endometrial hyperplasia are treatable. A common treatment is progestin, a manmade progesterone.
Does hyperplasia go away?
If left undiagnosed and untreated, endometrial hyperplasia will usually not abate on its own. Endometrial hyperplasia is often discovered because of abnormal uterine bleeding either between periods or after menopause.
How serious is endometrial hyperplasia?
Untreated atypical endometrial hyperplasia can become cancerous. Endometrial or uterine cancer develops in about 8% of women with untreated simple atypical endometrial hyperplasia. Close to 30% of women with complex atypical endometrial hyperplasia who don’t get treatment develop cancer.
What is the treatment for hyperplasia?
In many cases, endometrial hyperplasia can be treated with progestin. Progestin is given orally, in a shot, in an intrauterine device (IUD), or as a vaginal cream. How much and how long you take it depends on your age and the type of hyperplasia. Treatment with progestin may cause vaginal bleeding like a period.
How do you reduce hyperplasia?
Certain steps may reduce your chances of developing endometrial hyperplasia:
- Use progesterone along with estrogen after menopause (if you use hormone therapy).
- Take the birth control pill.
- Quit smoking.
- Maintain a healthy weight.
Is hyperplasia considered cancerous?
An increase in the number of cells in an organ or tissue. These cells appear normal under a microscope. They are not cancer, but may become cancer.
What is the most common age to get endometrial hyperplasia?
In our study, among women 18–90 years the overall incidence of endometrial hyperplasia was 133 per 100,000 woman-years, was most common in women ages 50–54, and was rarely observed in women under 30. Simple and complex hyperplasia incidences peaked in women ages 50–54.
Should I be worried about endometrial hyperplasia?
What is the treatment for endometrial hyperplasia?
Is hyperplasia curable?
In most cases, endometrial hyperplasia is very treatable. Work with your doctor to create a treatment plan. If you have a severe type or if the condition is ongoing, you might need to see your doctor more often to monitor any changes.