What are the side effects of Reglan?
Drowsiness, dizziness, tiredness, trouble sleeping, agitation, headache, and diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What is the most serious side effect of Reglan?
Neuroleptic Malignant Syndrome (NMS).
NMS is a very rare but very serious condition that can happen with REGLAN. NMS can cause death and must be 3 Page 4 treated in a hospital. Symptoms of NMS include: high fever, stiff muscles, problems thinking, very fast or uneven heartbeat, and increased sweating.
What are the serious side effects of metoclopramide?
Serious side effects
- Depression and suicide.
- Neuroleptic malignant syndrome (nervous system disorder).
- Tardive dyskinesia, a movement disorder that can be permanent.
- Parkinsonism (symptoms similar to those caused by Parkinson’s disease).
- Allergic reaction.
- Hyperprolactinemia (increased levels of the hormone prolactin).
What is contraindication of metoclopramide?
Metoclopramide is contraindicated in patients with depression because it can cause major depressive disorder. It is contraindicated in patients with seizures because it lowers the seizure threshold and can result in longer and more frequent seizures. It is contraindicated in patients with depression and …
What are the contraindications of Reglan?
Who should not take Reglan Injection?
- a high prolactin level.
- deficiency of the blood enzyme cytochrome b5 reductase.
- suicidal thoughts.
- a type of movement disorder called parkinsonism.
- tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue.
Is Reglan an antipsychotic?
Reglan (Metoclopramide) is a prescription drug for treating various digestive disorders. First developed as an antipsychotic in the 1960s, today it is mostly used to treat nausea, vomiting, heartburn, and similar conditions.
How do you treat metoclopramide side effects?
Intravenous anticholinergic benztropine is effective for most dystonic reactions within 5 minutes. Antihistamine, benzodiazepines, beta-adrenergic antagonists (propranolol), beta-adrenergic agonists (clonidine), or dopamine agonists (amantadine) may also be used .
What drug class is metoclopramide?
Reglan may be used alone or with other medications. Reglan belongs to a class of drugs called Antiemetic Agents; Prokinetic Agents.
What is the indication of metoclopramide?
Metoclopramide is used to treat the symptoms of slow stomach emptying (gastroparesis) in patients with diabetes. It works by increasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite.
Why do antipsychotics cause extrapyramidal side effects?
Antipsychotics block dopamine, which is what causes the extrapyramidal side effects in the first place. Anticholinergics increase dopamine so it becomes leveled out in your system.
What kind of medication is Reglan?
Reglan (metoclopramide) is a dopamine antagonist that is used as an antiemetic (anti-vomiting) agent used to treat nausea, vomiting, loss of appetite, heartburn and early satiety (feeling of fullness). Reglan is available in generic form.
What are extrapyramidal side effects?
Extrapyramidal side effects are a group of symptoms that can occur in people taking antipsychotic medications. 1 Symptoms of extrapyramidal effects include an inability to sit still, involuntary muscle contraction, tremors, stiff muscles, and involuntary facial movements.
How do you treat extrapyramidal side effects?
Anticholinergics can be given either orally or intramuscularly for more severe forms of extrapyramidal side effects, such as acute oculogyric crises or dystonias impairing a patient’s breathing. Trihexyphenidyl 2 to 8 mg per day and benztropine 2 to 8 mg per day are the most common anticholinergics given.
What is the action of metoclopramide?
It works by increasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite. Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD).
What are the 4 extrapyramidal symptoms?
What is extrapyramidal side effect?
Extrapyramidal side effects (EPS), commonly referred to as drug-induced movement disorders are among the most common adverse drug effects patients experience from dopamine-receptor blocking agents.
Which drugs cause extrapyramidal side effects?
Extrapyramidal symptoms, also called drug-induced movement disorders, describe the side effects caused by certain antipsychotic and other drugs.
What causes extrapyramidal symptoms?
What is the first line treatment for extrapyramidal symptoms?
Anticholinergic agents are a first-line treatment for drug-induced EPS, followed by amantadine. ECT is one of the most effective treatments for EPS.
Is metoclopramide an antacid?
REGLAN relieves daytime heartburn and heartburn after meals. It also helps ulcers in the esophagus to heal. to relieve symptoms of slow stomach emptying in people with diabetes. REGLAN helps treat symptoms such as nausea, vomiting, heartburn, feeling full long after a meal, and loss of appetite.
Why is it called extrapyramidal side effects?
Extrapyramidal symptoms (also called extrapyramidal side effects) get their name because they are symptoms of disorders in the extrapyramidal system, which regulates posture and skeletal muscle tone. This is in contrast to symptoms originating from the pyramidal tracts.
How do you manage extrapyramidal side effects?
Extrapyramidal symptoms caused by medication aren’t usually treated separately. Instead, your doctor may try a lower dose or a completely different medication. In some cases, a doctor may prescribe lipophilic beta-blockers, benzodiazepines, or anticholinergics to lessen the side effects of antipsychotic medications.
Is metoclopramide an antiemetic?
Metoclopramide is an anti-sickness medicine (known as an antiemetic). It’s used to help stop you feeling or being sick (nausea or vomiting) including: after radiotherapy or chemotherapy (treatment for cancer)
What are 7 drug classes of antiemetics?
Antiemetic drugs are medicines that ease nausea or vomiting.
Antiemetics that a doctor may prescribe after surgery include:
- dexamethasone (Decadron)
- droperidol (Inapsine)
- granisetron (Kytril)
- metoclopramide (Reglan)
- ondansetron (Zofran)
What are the 5 types of antiemetic drugs?
There are six different classes of FDA-approved antiemetic drugs:
- Neurokinin 1 (NK1) receptor antagonists.
- Serotonin receptor antagonists.
- Dopamine receptor antagonists.
What is the classification of antiemetic drugs?
The classes of antiemetics include antagonists of dopamine, serotonin, neurokinin, histamine and acetylcholine.